A baseball team made up of players from Prairie Elementary and Westwood View Elementary won the 3&2 Baseball 6th Grade division season title Sunday. The Warriors beat the Bees 10-5 in the final game to take the championship. The team is made up of (from left to right below) Peter Kohring, Ben Walburn,TJ Libeer, Nate Jones, Hatch and Stewart McCray, Ian Boyle Andrew Groat, Scott Nicolarsen, Dawson Borger, Wade Fugitt. (Thanks to Brian Libeer for the pic).
Vision researchers at Columbia University Medical Center have discovered a gene that causes myopia, but only in people who spend a lot of time in childhood reading or doing other “nearwork.”Using a database of approximately 14,000 people, the researchers found that those with a certain variant of the gene – called APLP2 – were five times more likely to develop myopia in their teens if they had read an hour or more each day in their childhood. Those who carried the APLP2 risk variant but spent less time reading had no additional risk of developing myopia.“We have known for decades that myopia is caused by genes and their interactions with environmental factors like reading and nearwork, but we have not had hard proof. This is the first known evidence of gene-environment interaction in myopia,” says the study’s lead investigator, Andrei Tkatchenko, MD, PhD, of CUMC. The research was published August 27 in PLOS Genetics. Share on Facebook Share on Twitter Pinterest Email Reducing APLP2 activity in eyes could prevent myopiaAlthough it’s not yet known how genetic variation at the APLP2 gene causes myopia, Dr. Tkatchenko and his colleagues think the risk variant may increase the amount of APLP2 protein produced in the eye, which in turn may cause the eye to undergo excessive elongation.They found that mice exposed to a visual environment that mimics reading were less likely to develop myopia when little APLP2 protein was present in the eye.“By reducing the level of APLP2 in the eye, you can reduce susceptibility to environmentally induced myopia. This gives us an opportunity to develop a therapy to prevent myopia in everyone, regardless of the APLP2 variant they carry,” Dr. Tkatchenko says.Developing such a therapy, however, could take years, as researchers don’t yet know how APLP2 levels could be reduced in people. And the therapy would be most effective in young children, before the eye has started to elongate and become myopic.“Once the eye has elongated, you cannot shrink it, so we would need to identify kids with genetic risk factors as they enter school,” Dr. Tkatchenko says. That’s not yet possible because there are probably hundreds of genes that can cause myopia, and so far, only 25 candidates have been identified. The high-risk variant of APLP2 is relatively uncommon, occurring in about 1 percent of the population.Outdoor time during childhood can reduce risk of developing myopiaThough a drug or gene therapy to prevent myopia may be years away, Dr. Tkatchenko says spending time outdoors is the best way to reduce kids’ risk of developing myopia.“We pretty much know all the environmental risk factors: time spent reading increases the risk, while time spent outdoors reduces it,” Dr. Tkatchenko says.Myopia rates have shot up in recent years due to changes in these environmental factors. In the U.S., 44 percent of adults are now nearsighted, up from 25 percent 30 years ago. And in some parts of Asia, 80 percent of young adults are now myopic.“The critical period for myopia development is during elementary and middle school, so when kids are in school, make sure they also spend at least two hours outdoors each day,” Dr.Tkatchenko says.Preventing myopia not only reduces the need for vision correction, but also prevents potentially blinding eye conditions later in life.“People say, ‘What’s so terrible about myopia? You just have to get glasses,’” Dr. Tkatchenko says, “But myopia increases the risk of developing cataracts, glaucoma, and retinal detachment later in life. All of these can lead to blindness.“Even in people with mild myopia there is a significant risk, but it’s especially high in people who need five or more diopters of vision correction (about 20/400 vision). That’s why it’s important to study myopia.” LinkedIn Share
2nd John batty (6) 30pts3rd Sang Roach (12) 29pts4th Mick Beresford (15) 27ptsB Flight1st Bob Mattes (18) 37pts2nd John Stafford (17) 32pts3rd Gerry Roach (22) 31pts4th Stefan Hoge (19) 31ptsLast week was our Lamlukka trip with 17 players. Day one was the mighty championship course of A & B, most players had never played it but A flight was playing off the yellow tees at 6,666 yards and thought they could conquer it. B flight went off the whites at 6,229 yards and the low scores in both flights said it all: great track in fantastic condition but very difficult.Wednesday, Sept. 6, Lamlukka G.C. – StablefordA Flight1st Steve Mann (12) 35pts2nd Phil Mitchell (6) 32pts3rd Paul Pavloff (7) 32pts4th Martin Grimoldby (5) 31ptsB Flight1st Bob Mattes (18) 33pts2nd Gerry Roach (22) 31pts3rd Stefan Hoge (19) 31pts4th Tim Knight (25) 29ptsMark Watkins thought he would be in the frame today with 17 points on the front nine but the wheels came off the back with only 10 on the inward half. Mick Beresford’s caddie forgot his putter on the second green and things went rapidly downhill for him from there.Steve Mann top scored for the day with 35 points and was three ahead of his closest pursuers in A flight. Bob Mattes took first place in B flight with 33 points with Gerry Roach taking the silver.Near pins went to John Stafford, Mark Watkins and Phil Mitchell. The Players Lounge Golf SocietyTuesday, Sept. 5, Lamlukka G.C. – StablefordA Flight1st Martin Grimoldby (5) 32pts
In this June 12, 2013 photo, Cincinnati Bengals cornerback Adam “Pacman” Jones rests during the NFL football team’s minicamp in Cincinnati. Photo / AP – Al Behrman, FilePacman’s sorry, AB.Cincinnati cornerback Adam “Pacman” Jones apologized Friday for claiming Pittsburgh Steelers wide receiver Antonio Brown was faking a concussion at the end of the wild-card game last Saturday night.The Steelers, who beat the Bengals on a late field goal, ruled Brown out for their divisional matchup Sunday with Denver after the two-time All-Pro was not cleared by doctors.Jones said in the aftermath of Cincinnati’s 18-16 loss that Brown winked at him before being helped off the field after taking a shot to the head from Bengals linebacker Vontaze Burfict.Jones posted a video on Instagram late Friday afternoon in which Jones said “I apologize sincerely. Get well.”Also Friday, Jones was fined $28,940 for contact with an official, a foul that moved the Steelers closer for their game-winning field goal in the final seconds.
Such amazing illustrations in @tmccarley ‘s talk on feedback. #IgniteUXMi pic.twitter.com/3wNMDJ5VvF— Justin Cohen (@JCosigner) March 15, 2016Feedback. The Skill You Need. slides by Tonya McCarleyOne Woman’s Heuristic Evaluation of HealthcarePresented by Josie ScottJosie has battled cancer for 20 years, and shared her humorous look at some of the UX issues of dealing with healthcare Insurance payments and medical records of services don’t match; what a frustrating UX to deal with!Ever been to the doctor and they won’t show you the screen with results of your test? Frustrating. Demand to see the screen.A Dive into Data to Understand Your Customer JourneyPresented by Diane BowenA customer journey map is like a movie, sharing a powerful storyHow do you start a customer journey map? Start with your goals.How can you better understand your user? Talk with your data analysts; get the user’s database, marketing, customer service points.A Dive into Data to Understand Your Customer Journey slides by Diane BowenStyle GuidePresented by Kavitha KrishnanUsers move between four core digital devices to accomplish a single goalStyle guides can help your users avoid having to relearn how to interact with your service or product By using style guides, you can create a consistent, continuous experience for your usersStyle guides are a living document, constantly evolvingYou Are Most Certainly, Definitely Not, Your UserPresented by Erik Wesslen When you have little in common with users, perhaps they live 10,000 miles away, where do you start?Your background, experience, and technology use are not your users’ background, experience or technology useThough you may feel you are like your user, you’re not! Do the user research. What a great evening of talks for Ignite UX Michigan 2016! Thanks to all who came out, our speakers and sponsors. #IgniteUXMI— Ignite UX Michigan (@IgniteUXmi) March 16, 2016 Earlier this month I had the pleasure of attending Ignite UX Michigan 2016, an evening of five-minute talks about user experience by local professionals and students.Organized by Mike Beasley, Whitney Ferdon, Andrea Neuhoff and their team of volunteers, over 160 people attending the March 15 event in Ann Arbor.It was an inspiring evening of usability-focused presentations! For many UX professionals and students, it was a reunion to see former colleagues. I had a great time catching up with friends. Here are my notes from some of the Ignite UX Michigan talks, along with social conversation and photos from the event:Excited to see you all there! Doors open at 6pm tonight for networking. Our program starts at 7pm. https://t.co/83bVmhzGR7 #ux— Ignite UX Michigan (@IgniteUXmi) March 15, 2016 Full house for #IgniteUXMI tonight! #UX #design pic.twitter.com/i7z7xgR4vz— Erik Wesslen (@erikwesslen) March 15, 2016Creating Experience by Telling StoriesPresented by Alina BochkachevaDesign with stories in your mind. No one wants to retell a bad story.By collecting the evidence and analyzing it, you’ll know what visualization to useStorytelling brings humanity to data; stories create relationships and connectionsClickable prototypes are not only great for usability testing, they’re great to check the storytellingMoments of JoyPresented by Christina YorkAugmented reality (AR) is technology that combines what is real with what is imaginaryWith AR, we’re creating moments of joy and escape for children in a hospital by changing perception of the moment, perception of the environment, and their engagement with treatmentAR can transform a hospital room into a scene from a book for kids, taking away their fear. Example: paper books come to 3D life.Moments of Joy slides by Christina YorkFeedback. The Skill You Need.Presented by Tonya McCarleyFeedback is hard. We need to get to the why.“We need to get out of the business of mind-reading.” Ask for clarification. Ask “Can you tell me more?” when you get feedbackIs your time best spent micromanaging design? Thank you to everyone that came to #igniteuxmi! Every year I’m blown away by how great this community is. pic.twitter.com/EqC8MJiyK5— Mike Beasley (@UXmikebeasley) March 16, 2016Shoutout to my friend Mike Wojan for allowing me to include his great photos from Ignite UX Michigan! Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Click to print (Opens in new window)Like this:Like Loading…RelatedRecap: Ignite UX Michigan 2014Ignite UX Michigan 2014 was a great success, with over 150 user experience professionals gathering in downtown Ann Arbor on October 22 for five-minute presentations focused on usability. Organized by Mike Beasley and Whitney Ferdon, it was an evening of inspiring talks and a reunion for UX professionals and students,…In “Event/meeting recap”Ignite UX Michigan 2017 Call for SpeakersDid your latest usability testing provide unexpected insights? Or have you taken a different approach in your team’s design critiques? Here’s your opportunity to share your lessons learned, thoughts, and experiences with fellow user experience professionals. Ignite UX Michigan 2017 has announced their call for speakers. For its fifth year,…In “User experience”It’s Back! Ignite UX Michigan Returns March 15Back for its fourth year, Ignite UX Michigan returns March 15, 2016 for a night of inspiring five-minute talks about user experience (UX). If you’re a UX professional, student, or someone interested in learning about user experience, it’s an event you don’t want to miss! Enjoy an evening of lively…In “Michigan”
Twitter: @Matt_RosenquistIntel Network: All My Previous Blog PostsLinkedIn: http://linkedin.com/in/matthewrosenquist Governor Brown of California signed an executive order (Order B-34-15) establishing a California Cybersecurity Integration Center (Cal-CSIC) to align and improve the posture and resilience of the state’s cybersecurity strategy. The CSIS will coordinate across state agencies and include federal government partners. It will create a Cyber Incident Response Team and secure mechanisms to properly share appropriate information.California is a massive state, with a huge economy, and heavily dependent on technology. Having a centralized capability to align and integrate resources is a fantastic concept. I applaud all the work which had to occur to get this legislation to this point. But the question remains, will the Cal-CSIC be a bureaucratic paper-tiger or will it have the necessary leadership, skills, and resources to forge a meaningful role in aligning a large and diverse team to prioritize and manage the state’s cyber risks?As a Californian and a cybersecurity professional, I truly hope this organization can become the beacon which forges effective alliances of the security teams across the state. Currently, separate organizations are working independently, without the benefit of strong coordination, to manage their cyber risks. The challenges are immense and put the state at considerable risk. Citizens of the state have high expectations. California, a longtime bastion of technology innovation, has been a leader in securing citizen’s privacy, life-safety practices, and environment protection. Cybersecurity overlays and binds all these aspects and can contribute to the health, prosperity, and safety of every Californian. This team will need very strong leadership to get all these groups to work together effectively. Otherwise it will become a detriment by adding unnecessary bureaucracy, without tangible benefits, to those groups trying to do the job independently. If California is able to get this right, it will be a huge win. If they get it wrong, it actually adds to the problems and hobbles all the current efforts underway. Governor Brown, move carefully, but with purpose. I urge you to forego political appointments or service based promotions, instead get the right functional experts in place and make this a reality to protect California. Find leaders with expert cybersecurity strategic insights, superb communication abilities, and practical industry experience necessary to earn the peer respect of the cross-functional team and the private sector partners. This will be a very tough job with ambitious goals, but if done properly, it has the potential to set California apart and showcase the state’s innovation and effectiveness in cybersecurity operations and internal governance as a standard for the nation and world.
TagsTransfersAbout the authorPaul VegasShare the loveHave your say Turkey coach Gunes worried about Tosun’s Everton situationby Paul Vegas14 days agoSend to a friendShare the loveTurkey coach Senol Gunes says Cenk Tosun’s situation at Everton is a concern.The Blues striker has been limited to just one appearance from the bench so far this season, picking up 35 minutes as Marco Silva’s side were beaten 2-0 by Sheffield United last month.Gunes said, “Cenk isn’t ready. He is on the bench at Everton for quite a while. “This isn’t a cool situation for us. We want him to play. But unfortunately, that’s not been the case for him at the moment. Hopefully, he will solve his situation soon.”Since making the move to Goodison Park in January 2018, the striker has scored nine goals in 45 appearances in all competitions.
zoom Crude oil tanker company DHT Holdings has entered into an agreement to sell its oldest very large crude carrier (VLCC), the 1999-built DHT Phoenix.The 307,200 dwt vessel was bought by an undisclosed shipowner for a price of USD 19.1 million, slightly over its market value of USD 18.4 million.DHT Holdings said that it will deliver the 332-meter-long crude carrier to its new owners during the second quarter of the year, when the ship is expected to retire from the trading fleet.The company added that the sale is in accordance with its fleet renewal strategy.The vessel has just completed a one year time charter deal at USD 45,000 per day to an Asian refining company.DHT Phoenix is debt free and the entire net proceeds will be added to the company’s cash balance. DHT Holdings expects to record a book loss of about USD 3.5 million in the first quarter of 2017 in connection with the sale.
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Login/Register With: Advertisement Twitter Advertisement Facebook Advertisement LEAVE A REPLY Cancel replyLog in to leave a comment In 2018 he published “Donald J. Trump: A President Like No Other.”Trump has also pardoned Patrick Nolan, a former Republican leader of the California State Assembly. Nolan has been a vocal advocate for criminal justice reform since he spent more than two years in federal prison during the 1990s. WASHINGTON – President Donald Trump has granted a full pardon to former Canadian media baron, Conrad Black, a former newspaper publisher who has written a flattering political biography of Trump.Black’s media empire once included the Chicago Sun-Times and The Daily Telegraph of London. He was convicted of fraud in 2007 and spent three and a half years in prison.White House press secretary Sarah Sanders says Black “has made tremendous contributions to business, and to political and historical thought.”